Global Cities

What cities are 'global cities' ? What is the meaning of global cities and how do they influence global culture? Some like Sassen state that global cities are 'command centers' for the global economy. Does this extend to centers of culture? Does New York, Los Angeles, London, Paris and Milan determine the global world culture? What are the roles of regional culture?
As the world is becoming more intergrated, is there a danger in the world becoming too homogenized? (This has been referred to as 'McDonaldlization'.) Is there a 'New Economy' developing?

These are some of the questions while I am in the process of preparing my upcoming article. I would appreciate any comments.

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